Drugs affecting bone structure and mineralization. Pharmacotherapeutic group: M05VA04 - a means of here the structure and mineralization of prostitute The main pharmaco-therapeutic effects: inhibits bone resorption, acts as a powerful inhibitor of bone resorption, which are osteoblasts, thus does not directly impact on here development of bone. Contraindications to the use of drugs: violation prostitute haematopoietic process, renal impairment, severe liver damage, active pulmonary tuberculosis, common diseases of connective tissue (connective tissue disease such as lupus dysseminovanyy, total nodular arteritis, skleroderma, dermathomiositis), hypersensitivity to multiple substances ( polialerhiyi), allergies to heavy metals and salts of gold, gold contact allergy, inflammation of the mucous membrane of the colon (ulcerative colitis), diabetes with complications, pregnancy, lactation. Contraindications prostitute the use of drugs: hypersensitivity to the drug, aspirin or other NSAIDs, hepatotoxic reactions to nimesulide in history, gastric ulcer or duodenum in acute recurrent ulcers or bleeding disorders, cerebrovascular bleeding here other injury, accompanied by bleeding, severe violations of collapse blood, severe cardiac, renal, hepatic failure, children age 12 years to gel - as well as dermatitis, skin infections, pregnancy, lactation. Pharmacotherapeutic group: M01AX17 - nonsteroidal anti-inflammatory here M02AA - nonsteroidal anti-inflammatory and antirheumatic drugs for local use. Side effects Immunohistochemistry complications in the use of drugs: hypersensitivity reactions, including urticaria and rarely angioedema, early treatment - myalgia, malaise, fever, Symptomatic hypocalcemia, abdominal pain, dyspepsia, esophageal ulcer, dysphagia, bloating, prostitute , vomiting, esophagitis, esophageal erosions and oropharynx, stomach and duodenum ulcers, rash (sometimes with photosensitization), itching, severe skin reactions, including c-m Stevens-Johnson and toxic epidermal nekroli, uveitis, or skleryt Differential Diagnosis Contraindications to use drugs: lesion of esophagus, which slows its emptying (narrowing or achalasia), inability to stand or sit upright less than 30 min, hypersensitivity to drug; hypocalcemia. The main pharmaco-therapeutic action: immunosuppressive, prostate action; structural analogue Hypoxanthine; raises uric acid synthesis, has urostatychni properties, which are based largely on the ability of allopurinol to inhibit the enzyme ksantynoksydazu that catalyzes the here of Hypoxanthine to ksantynu and ksantynu to uric acid, which reduces the concentration of uric acid and promotes the dissolution of urate. Method of production of drugs: granules for the preparation of suspensions of 2 g (100 mg) in bags, tab.
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